Supriya Ghosh (Editor)

Long range pseudoknots

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Rfam  RF01086
Domain(s)  Eukaryote Prokaryote
RNA type  Cis-reg
SO  {{{SO}}}
Long range pseudoknots

A long range pseudoknot is a pseudoknot containing a long loop region, and may be a mechanism of translational control.

A long range pseudoknot is thought to negatively regulate the translation of the IF3-L35-L20 operon in E. coli. This operon encodes the translation initiation factor IF-3 and ribosomal proteins L35 and L20. In this example, the RNA-RNA interaction occurs between nucleotides separated by a 300 nucleotide loop region.

A long range pseudoknot is also believed to be required for the activity of the Neurospora VS ribozyme.

References

Long range pseudoknots Wikipedia


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