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Long chain fatty acid—(acyl carrier protein) ligase

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EC number
  
6.2.1.20

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
77322-37-3

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a long-chain-fatty-acid-[acyl-carrier-protein] ligase (EC 6.2.1.20) is an enzyme that catalyzes the chemical reaction

ATP + an acid + [acyl-carrier-protein] AMP + diphosphate + acyl-[acyl-carrier-protein]

The 3 substrates of this enzyme are ATP, acid, and acyl-carrier-protein, whereas its 3 products are AMP, diphosphate, and [[acyl-[acyl-carrier-protein]]].

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming). Other names in common use include acyl-[acyl-carrier-protein] synthetase, acyl-[acyl carrier protein] synthetase, acyl-ACP synthetase, acyl-[acyl-carrier-protein]synthetase, stearoyl-ACP synthetase, and acyl-acyl carrier protein synthetase. This enzyme participates in fatty acid metabolism.

References

Long-chain-fatty-acid—(acyl-carrier-protein) ligase Wikipedia