Supriya Ghosh (Editor)

Latrophilin

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Symbol
  
Latrophilin

InterPro
  
IPR003334

PDB
  
RCSB PDB; PDBe; PDBj

Pfam
  
PF02354

Pfam
  
structures

PDBsum
  
structure summary

Latrophilins are a group of highly conserved G-protein coupled receptors from the adhesion G protein-coupled receptor family. These receptors were originally identified based on their ability to bind the spider venom alpha-latrotoxin. This conserved family of membrane proteins has up to three homologues in chordate species, including humans.

The precise functions of latrophilins remain unknown. Genetic defects in latrophilin genes have been associated with diseases such as attention-deficit hyperactivity disorder and cancer.

Human proteins containing this domain

  • Latrophilin 1 (LPHN1)
  • Latrophilin 2 (LPHN2)
  • Latrophilin 3 (LPHN3)
  • References

    Latrophilin Wikipedia


    Similar Topics