Symbol Latrophilin InterPro IPR003334 PDB RCSB PDB; PDBe; PDBj | Pfam PF02354 Pfam structures PDBsum structure summary | |
Latrophilins are a group of highly conserved G-protein coupled receptors from the adhesion G protein-coupled receptor family. These receptors were originally identified based on their ability to bind the spider venom alpha-latrotoxin. This conserved family of membrane proteins has up to three homologues in chordate species, including humans.
The precise functions of latrophilins remain unknown. Genetic defects in latrophilin genes have been associated with diseases such as attention-deficit hyperactivity disorder and cancer.
Human proteins containing this domain
References
Latrophilin Wikipedia(Text) CC BY-SA