Neha Patil (Editor)

Lamin B1

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Species
  
Human

Entrez
  
4001

Human
  
Mouse

Ensembl
  
ENSG00000113368

Lamin B1 aabcamcompsproducts133ab133741Imagesab1337

Aliases
  
LMNB1, ADLD, LMN, LMN2, LMNB, lamin B1

External IDs
  
MGI: 96795 HomoloGene: 55912 GeneCards: LMNB1

Bfp lamin b1 gfp tubulin 1b and rfp actin in triple tagged u2os cells


Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene.

Contents

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure, and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Lamin B, along with heterochromatin, is anchored to the inner surface of the nuclear membrane by the lamin B receptor.

Lamin B1 CST Lamin B1 D4Q4Z Rabbit mAb

Gene music using protein sequence of lmnb1 lamin b1


Interactions

LMNB1 has been shown to interact with Thymopoietin.

Lamin B1 Lamin B1 Antibody 129871AP Proteintech

Lamin B1 AntiLamin B1 antibody Nuclear Envelope Marker ab16048


Lamin B1 Lamin B1 is required for mouse development and nuclear integrity

References

Lamin B1 Wikipedia