CAS Number 23052-81-5 IUPHAR/BPS 1410 ECHA InfoCard 100.164.384 Molar mass 183.099 g/mol | PubChem CID 179394 ChemSpider 156157 Formula C4H10NO5P | |
 | ||
L-2-amino-4-phosphonobutyric acid (or L-AP4) is a drug used in scientific research, which acts as a group-selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8). It was the first ligand found to act as an agonist selective for this group of mGlu receptors, but does not show selectivity between the different mGluR Group III subtypes. It is widely used in the study of this receptor family and their various functions.
References
L-AP4 Wikipedia(Text) CC BY-SA