Kynurenine—glyoxylate transaminase

In enzymology, a kynurenine-glyoxylate transaminase (EC 2.6.1.63) is an enzyme that catalyzes the chemical reaction

L-kynurenine + glyoxylate ⇌ 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

Thus, the two substrates of this enzyme are L-kynurenine and glyoxylate, whereas its two products are 4-(2-aminophenyl)-2,4-dioxobutanoate and glycine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-kynurenine:glyoxylate aminotransferase (cyclizing). This enzyme is also called kynurenine-glyoxylate aminotransferase.