Kloss is a German surname. Some individuals with the surname include:
Cecil Boden Kloss (1877–1949), English zoologist
Dorothy Kloss (born 1923), Americal dancer
Eric Kloss (born 1949, American jazz saxophonist
Georg Kloss, (Georg Franz Burkhard Kloss, 1787–1854), German historian and early researcher in the history of freemasonry
Hans Kloss (artist) (born 1938), German painter and graphic artist
Hans Kloss (bank manager) (1905–1986), Austrian bank manager and lawyer
Hans Kloss (fictional character), a fictional World War II secret agent from the television series Stawka większa niż życie
Heinz Kloss (1904–1987), German sociolinguist
Henry Kloss (1929–2002), American audio engineer and entrepreneur
Ilana Kloss (born 1956), tennis player
Karlie Kloss (born 1992), American fashion model
Rieger–Kloss, pipe organ manufacturing company
