Kernaghan is a surname. Notable people with the surname include:
Alan Kernaghan (born 1967), professional football player and coach
Charles Kernaghan (born 1948), executive director of the Institute for Global Labour and Human Rights
Eileen Kernaghan (born 1939), Canadian novelist
Lee Kernaghan (born 1964), Australian country music singer and songwriter
Mae Kernaghan (1901-1980), former Republican member of the Pennsylvania House of Representatives
Mike Kernaghan (born 1955), lawn bowls competitor for New Zealand
Ray Kernaghan, Australian country music artist.
Tania Kernaghan (born 1968), Australian country music singer