Keeble is a surname. Notable people with the surname include:
Brian Keeble, authorCharles Keeble, Australian figure skaterChris Keeble, British Army veteranCurtis Keeble, British diplomatLady Constance Keeble, fictional character by P. G. WodehouseEdwin Augustus Keeble, 19th century U.S. politicianGeorge Keeble (1849–1923), English cricketerJim Keeble, British authorJoe Keeble, American football playerJohn Keeble, British pop musicianMarshall Keeble, U.S. preacherNoel Keeble, British World War I flyerSally Keeble, British Labour politicianSamantha Keeble, fictional character from British TV series EastendersVic Keeble, English footballerWoodrow W. Keeble, U.S. military veteran and recipient of Medal of Honor