Species Human Entrez 3763 | Human Mouse Ensembl ENSG00000157542 | |
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Aliases KCNJ6, BIR1, GIRK-2, GIRK2, KATP-2, KATP2, KCNJ7, KIR3.2, hiGIRK2, KPLBS, potassium voltage-gated channel subfamily J member 6 External IDs MGI: 104781 HomoloGene: 1688 GeneCards: KCNJ6 | ||
G protein-activated inward rectifier potassium channel 2 is a protein that in humans is encoded by the KCNJ6 gene.
Contents
Function
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
Interactions
KCNJ6 has been shown to interact with KCNJ9 and DLG1.
References
KCNJ6 Wikipedia(Text) CC BY-SA