Species Human Entrez 3748 | Human Mouse Ensembl ENSG00000131398 | |
Aliases KCNC3, KSHIIID, KV3.3, SCA13, potassium voltage-gated channel subfamily C member 3 External IDs MGI: 96669 HomoloGene: 3650 GeneCards: KCNC3 | ||
Potassium voltage-gated channel, Shaw-related subfamily, member 3 also known as KCNC3 or Kv3.3 is a protein that in humans is encoded by the KCNC3.
Contents
Function
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes.
Clinical significance
KCNC3 is associated with spinocerebellar ataxia type 13.
References
KCNC3 Wikipedia(Text) CC BY-SA