Jeffreys is a surname, which may refer to:
People: (See also the common variants Jeffries and Jefferies)
Alec Jeffreys (born 1950), British biologist and discoverer of DNA fingerprinting
Anne Jeffreys (born 1923), American actress & singer
Arthur Frederick Jeffreys (1848–1906), British politician
Bertha Jeffreys (1903–1999), British physicist a.k.a. Bertha Swirles
Charles Jeffreys (1877 – unknown), South African shooter
Elizabeth Jeffreys (born 1941), British Byzantinist
Ellen Penelope Jeffreys (1827–1904), New Zealand artist
Garland Jeffreys (born 1943), American musician
George Jeffreys (composer) (c. 1610 – 1685), composer and organist to Charles I
George Jeffreys, 1st Baron Jeffreys (1645–1689), British jurist & politician
George Jeffreys, 1st Baron Jeffreys (second creation) (1878–1960), British soldier & politician
George Jeffreys (pastor) (1889–1962), British religious leader
Gina Jeffreys (born 1968), Australian singer
Harold Jeffreys (1891–1989), British mathematician, statistician, geophysicist and astronomer
J. G. Jeffreys (born 1893), Australian-born educator
John Gwyn Jeffreys (1809–1885), British malacologist
John R. F. Jeffreys (1918–1944), British mathematician
Julius Jeffreys (1800–1877), British physician
Paul Jeffreys (1952–1988), English rock musician and bassist
Rhodri Jeffreys-Jones (born 1942), British historian
Robin Jeffreys (1890–1963), British Olympic fencer
Sheila Jeffreys (born 1948), British-born political scientist, academic, & activist
Stephen Jeffreys (born 1950), British playwright
Other:
Baron Jeffreys, a title in the English and UK peerages
