James Lee may refer to:
James Lee (cricketer, born 1838) (1838–1880), Yorkshire cricketer during the 1880s
James Lee (cricketer, born 1988), Yorkshire cricketer during the 2000s
James Lee (defensive tackle) (1980–2016), American football player
James Lee (offensive lineman) (born 1985), American football player
James Lee (basketball) (born 1956), American basketball player
Tancy Lee (1882–1941), Scottish boxer born James Lee
James P. Lee (1870–1941), American football player
James Prince Lee (1804–1869), English clergyman who became the first Bishop of Manchester
James Yusuf Lee, Guantanamo chaplain
James Lee (1715–1795), Scottish nurseryman, of Lee and Kennedy
James H. Lee (1840–1877), American sailor and Medal of Honor recipient
James Nelson Lee (c. 1923–2014), American judge
James Paris Lee (1831–1904), Canadian inventor
James Yimm Lee (1920–1972), martial arts author
James Lee (Canadian politician) (born 1937), Prince Edward Island politician
James Lee (Malaysian film director) (born 1973), Malaysian film director and producer
James Lee (screenwriter) (1923–2002), American screenwriter
James Lee (writer) (born 1947), Singaporean writer
James Lee (vocalist), vocalist for the death metal band Origin
James Jay Lee, perpetrator in the 2010 Discovery Communications headquarters hostage crisis
James Kyson Lee (born 1975), Korean-born American actor
James B. Lee, Jr. (1952–2015), investment banker
