James August Comiskey (October 16, 1926 – February 1, 2005) was a United States federal judge.
Born in New Orleans, Louisiana, Comiskey was in the United States Army during World War II, from 1944 to 1946. He received a B.A. from Loyola University New Orleans in 1949 and a J.D. from Loyola University New Orleans School of Law in 1951. He was in private practice in New Orleans from 1951 to 1967.
On January 16, 1967, Comiskey was nominated by President Lyndon B. Johnson to a new seat on the United States District Court for the Eastern District of Louisianacreated by 80 Stat. 75. He was confirmed by the United States Senate on March 2, 1967, and received his commission on March 4, 1967. Comiskey served in that capacity until his resignation on June 15, 1975.
He was thereafter in private practice in New Orleans until his death in that city, in 2005.