In his early career, Skrzek was associated with the groups Ślężanie, Ametysty and Breakout. In 1971, he created the progressive-rock group Silesian Blues Band (with Jerzy Piotrowski and Apostolis Anthimos) and also recorded for a time with Czesław Niemen.
Over the following decades, Skrzek consistently showed independence. He performed with a number of artist and ad hoc created bands, but mostly involved himself with theater and church music, as well as movie soundtracks. He is well-noted for his live performances not only on conventional concerts but also in a variety of other venues (e.g., his improvisations on summer solstice nights in Silesian Planetarium). Currently, he is a friend of the elementary school in his hometown (elementary school number 13 in Michalkowice) where he often plays or sings.
In 2012 together with Jarosław Pijarowski and his (pl:Teatr Tworzenia) created the first Polish avantgarde oratorio "Terrarium"(pl:Terrarium – Live in Bydgoszcz).
His younger brother, Jan Skrzek (pl:Jan Skrzek), was also a notable Silesian musician.