Suvarna Garge (Editor)

Isoflavonoid biosynthesis

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The biosynthesis of isoflavonoids involves several enzymes; These are:

Liquiritigenin,NADPH:oxygen oxidoreductase (hydroxylating, aryl migration), also known as Isoflavonoid synthase, is an enzyme that uses liquiritigenin (a flavanone), O2, NADPH and H+ to produce 2,7,4'-trihydroxyisoflavanone (an isoflavonoid), H2O and NADP+.

  • Biochanin-A reductase
  • Flavone synthase
  • 2'-hydroxydaidzein reductase
  • 2-hydroxyisoflavanone dehydratase
  • 2-hydroxyisoflavanone synthase
  • Isoflavone 4'-O-methyltransferase
  • Isoflavone 7-O-methyltransferase
  • Isoflavone 2'-hydroxylase
  • Isoflavone 3'-hydroxylase
  • Isoflavone-7-O-beta-glucoside 6"-O-malonyltransferase
  • Isoflavone 7-O-glucosyltransferase
  • 4'-methoxyisoflavone 2'-hydroxylase

    • Pterocarpans biosynthesis

  • 3,9-dihydroxypterocarpan 6a-monooxygenase
  • Glyceollin synthase
  • Pterocarpin synthase

    • References

    Isoflavonoid biosynthesis Wikipedia
    (Text) CC BY-SA