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Irwin Fridovich

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Residence
  
Durham, North Carolina

Name
  
Irwin Fridovich

Citizenship
  
United States

Fields
  
Doctoral advisor
  
Institutions
  

Irwin Fridovich httpsuploadwikimediaorgwikipediacommonsthu

Born
  
August 2, 1929New York City (
1929-08-02
)

Alma mater
  
Doctoral students
  
Books
  
Oxy-Radicals in Molecular Biology and Pathology

Education
  
Duke University, City College of New York

Known for
  
People also search for
  
Joe M. McCord, Philip Handler, Hara P. Misra

Notable awards
  

Irwin fridovich 2014


Irwin Fridovich is an American biochemist who, together with his graduate student Joe M. McCord, discovered the enzymatic activity of copper,zinc superoxide dismutase (SOD),β€”to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct of normal oxygen metabolism. Subsequently, Fridovich's research group also discovered the manganese-containing and the iron-containing SODs from E coli and the mitochondrial MnSOD (SOD2), now known to be an essential mammalian protein. He spent the rest of his career studying the biochemical mechanisms of SOD and of biological superoxide toxicity, using bacteria as model systems. Fridovich is currently Professor Emeritus of Biochemistry at Duke University.

Contents

Irwin Fridovich httpswwwbiochemdukeedusiteswwwbiochemduk

Academic career

From 1951 to 1952, Fridovich served as a medical research associate at Cornell Medical College. He held junior teaching positions in biochemistry at Duke University 1956 to 1961 and was a visiting research associate at Harvard University from 1961 to 1962. He became an assistant professor in biochemistry at Duke University in 1961 and a full professor in 1971. He was appointed as James B. Duke Professor of Biochemistry in 1976 and has held the position as professor emeritus since 1996.

Awards and honors

Fridovich has received numerous awards and recognitions for his work, including membership in the National Academy of Sciences and the American Academy of Arts and Sciences, and the Elliott Cresson Medal of the Franklin Institute, Philadelphia. According to Google Scholar, he has over 51,000 citations in the scientific literature, including 7 papers with >1000 citations, and an H-index of 97. His discovery of the superoxide dismutase reaction essentially started the field of oxygen free radicals in biology and medicine, and that influence is shown by his election as president of the American Society of Biological Chemists (for 1982–83)[1], the Oxygen Society (1987–1990), and the Society for Free Radical Research (1992–94), as well as award of the Science & Humanity Prize at the 2000 Oxygen Club World Congress.

References

Irwin Fridovich Wikipedia