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Ionomycin

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Calcium efflux fluo 3 from a glomerulus ionomycin


Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus. It is used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. It is also used to stimulate the intracellular production of the following cytokines; interferon, perforin, IL-2, and IL-4 - usually in conjunction with PMA. These cytokines are important in the inflammatory response.

Contents

Commercially, Ionomycin can be obtained as a free acid, or as a Ca2+ salt.

Medical vocabulary what does ionomycin mean


References

Ionomycin Wikipedia