EC number 3.4.24.7 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 2593923 BRENDA BRENDA entry KEGG KEGG entry | |
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Interstitial collagenase (EC 3.4.24.7, vertebrate collagenase, matrix metalloproteinase 1) is an enzyme. This enzyme catalyses the following chemical reaction
Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile in the alpha1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue
This enzyme belongs to the peptidase family M10.
References
Interstitial collagenase Wikipedia(Text) CC BY-SA