Entrez 26525 | Ensembl ENSG00000136695 | |
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Aliases IL36RN, FIL1, FIL1(DELTA), FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, PSORP, IL-36Ra, PSORS14, interleukin 36 receptor antagonist External IDs MGI: 1859325 HomoloGene: 10453 GeneCards: IL36RN | ||
Interleukin 36 receptor antagonist is a protein that in humans is encoded by the IL36RN gene. It was previously named Interleukin-1 family member 5 (IL1F5).
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported.
References
Interleukin 36 receptor antagonist Wikipedia(Text) CC BY-SA