HUGO 5988 RefSeq NM_003855 | Entrez 8809 OMIM 604494 | |
Alt. symbols IL1RRP, IL-1Rrp, CD218a |
The interleukin-18 receptor (IL-18R) is an interleukin receptor of the immunoglobulin superfamily. IL-18R is a heteromeric complex of alpha- and beta-chains encoded by the genes IL18R1 and IL18RAP respectively.
Endometrial IL-18 receptor mRNA and the ratio of IL-18 binding protein to interleukin 18 are significantly increased in adenomyosis patients in comparison to normal people, indicating a role in its pathogenesis.
References
Interleukin-18 receptor Wikipedia(Text) CC BY-SA