Type Whole antibody Trade names Prostascint CAS Number 151763-64-3 | Source Mouse ATC code V09IB04 (WHO) | |
Target prostatic carcinoma cells | ||
Indium (111In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer. Capromab is a mouse monoclonal antibody which recognizes prostate specific membrane antigen (PSMA) from prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA. Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single photon emission computed tomography (SPECT).
Early trials with yttrium (90Y) capromab pendetide were also conducted.
References
Indium (111In) capromab pendetide Wikipedia(Text) CC BY-SA