Samiksha Jaiswal (Editor)

IRF2

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Species
  
Human

Entrez
  
3660

Human
  
Mouse

Ensembl
  
ENSG00000168310

IRF2 wwwnaturecomngjournalv44n6imagesng2256F4jpg

Aliases
  
IRF2, IRF-2, interferon regulatory factor 2

External IDs
  
MGI: 96591 HomoloGene: 1659 GeneCards: IRF2

Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.

Contents

Function

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.

Interactions

IRF2 has been shown to interact with BRD7, EP300 and PCAF.

References

IRF2 Wikipedia