Samiksha Jaiswal (Editor)

IRF2

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Species
  
Human

Entrez
  
3660

Human
  
Mouse

Ensembl
  
ENSG00000168310

IRF2 wwwnaturecomngjournalv44n6imagesng2256F4jpg

Aliases
  
IRF2, IRF-2, interferon regulatory factor 2

External IDs
  
MGI: 96591 HomoloGene: 1659 GeneCards: IRF2

Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.

Contents

Function

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.

Interactions

IRF2 has been shown to interact with BRD7, EP300 and PCAF.

References

IRF2 Wikipedia
(Text) CC BY-SA


Similar Topics