Species Human Entrez 3660 | Human Mouse Ensembl ENSG00000168310 | |
Aliases IRF2, IRF-2, interferon regulatory factor 2 External IDs MGI: 96591 HomoloGene: 1659 GeneCards: IRF2 |
Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.
Contents
Function
IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
Interactions
IRF2 has been shown to interact with BRD7, EP300 and PCAF.
References
IRF2 Wikipedia(Text) CC BY-SA