Species Human Entrez 3656 | Human Mouse Ensembl ENSG00000134070 | |
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Aliases IRAK2, IRAK-2, interleukin 1 receptor associated kinase 2 External IDs MGI: 2429603 HomoloGene: 1207 GeneCards: IRAK2 | ||
Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene.
Contents
Function
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
Interactions
IRAK2 has been shown to interact with TRAF6 and Myd88.
References
IRAK2 Wikipedia(Text) CC BY-SA