Puneet Varma (Editor)

IRAK1

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Species
  
Entrez
  
3654

Human
  
Ensembl
  
ENSG00000184216

IRAK1

Aliases
  
IRAK1, IRAK, pelle, interleukin 1 receptor associated kinase 1

External IDs
  
MGI: 107420 HomoloGene: 37496 GeneCards: IRAK1

Interleukin-1 receptor-associated kinase 1 is an enzyme that in humans is encoded by the IRAK1 gene.

Contents

Function

This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Interactions

IRAK1 has been shown to interact with:

References

IRAK1 Wikipedia


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