Species Human Entrez 3654 | Human Mouse Ensembl ENSG00000184216 | |
 | ||
Aliases IRAK1, IRAK, pelle, interleukin 1 receptor associated kinase 1 External IDs MGI: 107420 HomoloGene: 37496 GeneCards: IRAK1 | ||
Interleukin-1 receptor-associated kinase 1 is an enzyme that in humans is encoded by the IRAK1 gene.
Contents
Function
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Interactions
IRAK1 has been shown to interact with:
References
IRAK1 Wikipedia(Text) CC BY-SA