Girish Mahajan (Editor)

INTS1

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Species
  
Human

Entrez
  
26173

Human
  
Mouse

Ensembl
  
ENSG00000164880

Aliases
  
INTS1, INT1, NET28, integrator complex subunit 1

External IDs
  
MGI: 1915760 HomoloGene: 53111 GeneCards: INTS1

Gene music using protein sequence of ints10 integrator complex subunit 10


Integrator complex subunit 1 is a protein that in humans is encoded by the INTS1 gene.

Contents

Gene music using protein sequence of ints12 integrator complex subunit 12


Function

INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).

References

INTS1 Wikipedia