Entrez 3621 | Ensembl ENSG00000153487 | |
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Aliases ING1, p24ING1c, p33, p33p33ING1b, p47, p47ING1a, inhibitor of growth family member 1 External IDs MGI: 1349481 HomoloGene: 40119 GeneCards: ING1 | ||
Gene music using protein sequence of ing1 inhibitor of growth family member 1
Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene.
Contents
- Gene music using protein sequence of ing1 inhibitor of growth family member 1
- Function
- Location on Chromosome 13
- Interactions
- References
Function
This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Location on Chromosome 13
ING1 is located near the following genes on Chromosome 13
Interactions
ING1 has been shown to interact with:
References
ING1 Wikipedia(Text) CC BY-SA