Species Human Entrez 55540 | Human Mouse Ensembl ENSG00000056736 | |
 | ||
Aliases IL17RB, CRL4, EVI27, IL17BR, IL17RH1, interleukin 17 receptor B External IDs MGI: 1355292 HomoloGene: 10287 GeneCards: IL17RB | ||
Interleukin-17 receptor B is a protein that in humans is encoded by the IL17RB gene.
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17(A) or IL17C. This receptor has been shown to mediate the activation of NF-κB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
References
IL17RB Wikipedia(Text) CC BY-SA