Hypotaurine dehydrogenase

In enzymology, a hypotaurine dehydrogenase (EC 1.8.1.3) is an enzyme that catalyzes the chemical reaction

The 3 substrates of this enzyme are hypotaurine, H₂O, and NAD⁺, whereas its 3 products are taurine, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hypotaurine:NAD+ oxidoreductase. This enzyme participates in taurine and hypotaurine metabolism. It has 2 cofactors: heme, and Molybdenum.