Hyer is a surname. Notable people with the surname include:
Alex M. Hyer, 19th-century American politicianBruce Hyer (born 1946), Canadian politicianDavid Hyer (1875–1942), American architectJacob Hyer (died 1838), American bare-knuckled boxerMartha Hyer (1924–2014), American actressPaul Hyer (born 1926), American academicRobert Stewart Hyer (1860–1929), American educator and researcherTom Hyer (1819–1864), American bare-knuckle boxer