Hulme is a surname. Notable people with the surname include:
Alan Hulme (1907–1989), Australian politician
Alfred Hulme (1911–1982), New Zealand recipient of the Victoria Cross
Darren Hulme (born 1977), former Australian rules footballer
David Hulme (rugby league), British rugby league footballer
David Russell Hulme (born 1951), Welsh conductor and musicologist
Denny Hulme (1936–1992), New Zealand car racer, F1 world champion
Etta Hulme (born 1923), syndicated editorial cartoonist
F. Edward Hulme (1841–1909), English artist and botanist
Joe Hulme (1904–1991), English footballer and cricketer
John Hulme (cricketer, born 1862), (1862–1940)
John Hulme (cricketer, born 1950) (1950–)
John Hulme (author) (c. 1970–)
Anne Perry (born 1938 as Juliet Hulme), English author of historical detective fiction
Kathryn Hulme (1900–1981), American novelist
Keri Hulme (born 1947), New Zealand writer
Lachy Hulme (born 1971), Australian film actor
Mark Hulme (born 1958), American movie producer and entrepreneur
T. E. Hulme (1883–1917), English writer
W. Wilson Hulme II (1946–2007), Curator of the National Postal Museum
William Hulme (circa 1631–1691), English lawyer
William Hulme (British Army officer) (died 1855), Manchester Regiment officer