Huff is a surname. Notable people with the surname include:
Aubrey Huff (born 1976), baseball player
Bob Huff (born 1953), American politician
Brent Huff (born 1961), American actor, writer and film director
Dann Huff (born 1960), singer, guitarist, songwriter and producer, and foundation member of 80s hard rock band Giant
Darrell Huff (1913–2001), economist and author of How to Lie with Statistics
David Huff (musician), drummer (born 1961), songwriter and record producer, and foundation member of Giant along with brother Dann
David Huff (baseball) (born 1984), baseball player
Gail Huff, reporter for Boston's WCBV-TV, and wife of U.S. Senator Scott Brown
Gene Huff, American politician
George Huff (coach) (1872–1936), American athlete and coach; manager of the Boston Red Sox
George Huff (singer) (born 1980), American singer
Janice Huff (born 1960), meteorologist and TV anchor person
Leon Huff (born 1942), afro-American songwriter and record producer with Kenneth Gamble as Gamble and Huff
Michael Huff (born 1983), American footballer
Orlando Huff (born 1978), American footballer
Paul B. Huff (1918–1994), Medal of Honor recipient
Sam Huff aka Robert Lee Huff (born 1934), American footballer, coach and commentator
Tanya Huff (born 1957), Canadian fantasy author
Thomas Huff, co-founder of Huff-Daland Aero Corp
Tom Huff (American politician), American state legislator
Warren D. Huff, professor of geology at the University of Cincinnati