Neha Patil (Editor)

HtrA2 peptidase

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EC number
  
3.4.21.108

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

HtrA2 peptidase (EC 3.4.21.108, high temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, serine proteinase OMI, OMI/HtrA2 protease, HtrA2/Omi, Omi/HtrA2) is an enzyme. This enzyme catalyses the following chemical reaction

Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met.

This enzyme is upregulated in mammalian cells in response to stress induced by heat shock and tunicamycin treatment.

References

HtrA2 peptidase Wikipedia