Rahul Sharma (Editor)

Homogentisic acid

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Formula
  
C8H8O4

Molar mass
  
168.1467 g/mol

Homogentisic acid httpsuploadwikimediaorgwikipediacommonsthu

Homogentisic acid oxidase deficiency spanish meaning


Homogentisic acid (2,5-dihydroxyphenylacetic acid) is a phenolic acid found in Arbutus unedo (strawberry-tree) honey. It is also present in the bacterial plant pathogen Xanthomonas campestris pv. phaseoli as well as in the yeast Yarrowia lipolytica where it is associated with the production of brown pigments.

Contents

It is less commonly known as melanic acid, the name chosen by William Prout.

Homogentisic acid oxidase deficiency arabic meaning


Human pathology

Accumulation of excess homogentisic acid and its oxide, named alkapton, is a result of the failure of the enzyme homogentisic acid 1,2-dioxygenase (typically due to a mutation) in the degradative pathway of tyrosine, consequently associated with alkaptonuria.

Intermediate

It is an intermediate in the catabolism of aromatic amino acids such as phenylalanine and tyrosine.

References

Homogentisic acid Wikipedia