Species Human Entrez 3206 | Human Mouse Ensembl ENSG00000253293 | |
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Aliases HOXA10, HOX1, HOX1.8, HOX1H, PL, Homeobox A10 External IDs MGI: 96171 HomoloGene: 7365 GeneCards: HOXA10 | ||
Homeobox protein Hox-A10 is a protein that in humans is encoded by the HOXA10 gene.
Contents
Function
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.
Interactions
Homeobox A10 has been shown to interact with PTPN6.