Rahul Sharma (Editor)

Homatropine

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AHFS/Drugs.com
  
Monograph

CAS Number
  
87-00-3

Molar mass
  
356.26 g/mol

MedlinePlus
  
a601006

PubChem CID
  
6321423

CAS ID
  
80-49-9

Homatropine

ATC code
  
A02BX03 (WHO) S01FA05 (WHO)

Legal status
  
Rx only, not FDA approved, only sold in UK

Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation), and as a mydriatic (to dilate the pupil). For Homatropine methylbromide see Methylhomatropine, this is a different medication. Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide salt.

Contents

Homatropine is also given as an atropine substitute given to reverse the muscarinic and CNS effects associated with indirect cholinomimetic (anti-AChase) administration.

Side effects

  • Blurred vision
  • Sensitivity to light
  • Contraindications

  • Untreated glaucoma
  • Myasthenia gravis
  • Severe heart failure
  • Thyrotoxicosis
  • References

    Homatropine Wikipedia


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