Reinhorn was born and raised in Portland, Oregon. She is a graduate of the Iowa Writers' Workshop and the author of Big Cats, published by Free Press in 2005. Her work has been published in Ploughshares, Zoetrope: All-Story, Gulf Coast, and many other literary magazines.
She is married to actor Rainn Wilson, whom she met while both were students at the University of Washington. The couple married on the Kalama River in Washington in 1995. They are both adherents of the Bahá'í Faith.