Holdsworth is a surname. Notable people with the surname include:
Holdsworth (Yorkshire cricketer), 19th century English cricketer
Allan Holdsworth (born 1946), English guitarist and composer
Andy Holdsworth (born 1984), English footballer
Annie E. Holdsworth, English writer
Arthur Howe Holdsworth (1780–1860), English merchant and politician
B. G. Holdsworth (1892–1949), Indian civil servant
Dame Bronwen Holdsworth (born 1943), New Zealand businesswoman and arts patron
Chris Holdsworth (born 1987), American mixed martial artist
Daniel Holdsworth (disambiguation), multiple people
David Holdsworth (born 1968), English footballer and manager
Dean Holdsworth (born 1968), English footballer and manager
Edward Holdsworth (1684–1746), English classical scholar
Ethel Carnie Holdsworth (1886–1962), English writer
Frank Holdsworth (1872–1941), New Zealand cricketer
Frank Wild Holdsworth (1904–1969), British orthopaedic surgeon
Fred Holdsworth (born 1952), American baseball player
Gary Holdsworth (born 1941), Australian sprinter
Herbert Holdsworth (1890–1949), British politician and businessman
James B. Holdsworth (c. 1796 – 1859), Canadian merchant and politician
Jeff Holdsworth (born 1963), American musician
Jim Holdsworth (1850–1918), American baseball player
John Holdsworth, English rugby league referee
John Holdsworth (rugby union) (1884–?), Australian rugby union player
Kelvin Holdsworth (born 1966), Scottish Episcopalian clergyman
Lee Holdsworth (born 1983), Australian racing driver
Paul Holdsworth (born 1970), Australian rules footballer
Petrina Holdsworth (born 1952), English politician
Philip Holdsworth (1851–1902), Australian poet and public servant
Richard Holdsworth (1590–1649), English academic theologian
R. L. Holdsworth (1899–1976), British academic and explorer
Ted Holdsworth (born 1984), Australian rules footballer
Trevor Holdsworth (1927–2010), English businessman
Wayne Holdsworth (born 1968), Australian cricketer
William Holdsworth (disambiguation), multiple people