Hexestrol

Hexestrol (INN) (brand name Synestrol, Synoestrol, Estrifar, Estronal, numerous others), also known as hexanestrol, hexoestrol, and dihydrodiethylstilbestrol, is a synthetic, non-steroidal estrogen of the stilbestrol group related to diethylstilbestrol that was used to treat estrogen deficiency but is now no longer employed medically. Hexestrol has also been available and used in ester form, including as hexestrol diacetate, hexestrol dicaprylate, hexestrol diphosphate, and hexestrol dipropionate. Hexestrol has approximately 302% and 234% of the affinity of estradiol at the ERα and ERβ, respectively. Along with diethylstilbestrol, hexestrol is one of the most potent estrogens known.

Contents

• The effects of hexestrol on mammalian animals
• The effects of hexestrol on mouse ovarian morphology and ovulation
• References