Puneet Varma (Editor)

Hesperetin

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Formula
  
C16H14O6

Molar mass
  
302.27 g/mol

Hesperetin httpsuploadwikimediaorgwikipediacommonsthu

What does hesperetin mean


Hesperetin (5,7,3',4'-OMe-flavan-on) is the 4'-methoxy derivative of eriodictyol, a flavanone. Hesperetin's 7-O-glycoside, hesperidin, is a naturally occurring flavanon-glycoside, the main flavonoid in lemons and sweet oranges. Hesperetin (and naringenin, the parent flavanone of naringin) are not found to a significant extent in Citrus spp.

Contents

How to pronounce hesperetin


Glycosides

A variety of glycosides of hesperetin are known, including:

  • Hesperidin (hesperetin-7-O-rutinoside) is a water－insoluble flavonoid glycoside whose solubility is below 5 μg/ml in water. Hesperidin is found in citrus fruits and upon ingestion it releases its aglycone, hesperetin.
  • Neohesperidin is the 7-O-neohesperidoside of hesperetin.
  • Hesperetin-7-O-α-L-Rhamnopyranoside (CAS 66513-83-5) is found in the roots of clammy cherry (Cordia obliqua a.k.a. Cordia obliqua var. wallichii).

    • Metabolism

    Hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase is an enzyme that uses hesperidin and H2O to produce hesperetin and rutinose. It is found in the hyphomycetes species Stilbella fimetaria.

    References

    Hesperetin Wikipedia
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