Specialty endocrinology ICD-9-CM 277.4 MeSH D006933 | ICD-10 E80.4-E80.6 eMedicine med/1065 med/1066 | |
Hereditary hyperbilirubinemia refers to the condition where levels of bilirubin are elevated, for reasons that can be attributed to a metabolic disorder.
An example is Crigler-Najjar syndrome.
Symptoms
UGT1A1 gene mutations causes the condition. As a result, there can be reduced functionality of the bilirubin-UGT enzyme. Eventually it causes unconjugated hyperbilirubinemia and jaundice as substance accumulates in the body due to the reduced ability of the enzyme.
References
Hereditary hyperbilirubinemia Wikipedia(Text) CC BY-SA