Samiksha Jaiswal


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Specialty  oncology, rheumatology
ICD-O  M9150/1
eMedicine  orthoped/500
ICD-10  C49 (ILDS C49.M20)
DiseasesDB  29249
MeSH  D006393

A hemangiopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the walls of capillaries. When inside the nervous system, although not strictly a meningioma tumor, it is a meningeal tumor with a special aggressive behavior. It was first characterized in 1942.



Hemangiopericytoma located in the cerebral cavity is an aggressive tumor of the Mesenchyme with oval nuclei with scant cytoplasm. "There is dense intercellular reticulin staining. Tumor cells can be fibroblastic, myxoid, or pericytic. These tumors, in contrast to meningiomas, do not stain with epithelial membrane antigen. They have a grade 2 or 3 biological behavior, and need to be distinguished from benign meningiomas because of their high rate of recurrence (68.2%) and metastases (Maier et al. 1992; Kleihues et al. 1993 )."


Depending on the grade of the sarcoma, it is treated with surgery, chemotherapy and/or radiotherapy.


The word hemangiopericytoma comes from the ancient Greek words: haema (combining form of Ancient Greek αἷμα, haîma, “blood”), angio- (means blood vessel), angioma, peri- (prefix meaning “about” or “around”, “enclosing” or “surrounding”, and “near”, appearing in loanwords from Greek; and -cytoma (refers to the cells surrounding the blood vessel walls).


Hemangiopericytoma Wikipedia

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