Slocum was born in Baton Rouge, Louisiana. He attended St. Anthony of Padua Catholic School in Bunkie, Louisiana from 1986 (6th grade) until 1987 (8th grade). Slocum learned the game of golf from his father, Jack. He played on the same Milton High School golf team in Milton, Florida as fellow PGA Tour player Boo Weekley, and later attended the University of South Alabama in Mobile, Alabama. While a student there, he earned many amateur golf honors including three-time All-American. He turned professional in 1996.
Slocum began his career on the Web.com Tour, then known as the Nike Tour. In November 1997, Slocum developed ulcerative colitis which caused his weight to drop from 150 pounds to 122 pounds, and left him unable to play for a year and a half. The Crohn's & Colitis Foundation of America named Slocum a national spokesperson, to help raise awareness of ulcerative colitis and Crohn's disease, another inflammatory bowel disease.
After he recovered, Slocum regained his playing privileges on the Web.com Tour in 2000. In 2001, he became the second player to earn a "battlefield promotion" to the PGA Tour by winning three Web.com Tour events in the same season, and only the second player in Web.com Tour history to complete 72 holes without a bogey.
Slocum joined the PGA Tour in 2001, and has four wins in his career. His first win was in 2004 at the Chrysler Classic of Tucson. His second win came at the Southern Farm Bureau Classic in 2005. His best finish in a major is a tie for 9th at the 2008 U.S. Open and he has featured in the top 100 of the Official World Golf Ranking.
Slocum represented the United States at the 2007 World Cup, partnered with Boo Weekley. The Americans finished second after losing a sudden-death playoff to Scotland.
Slocum barely qualified for the 2009 FedEx Cup Playoffs; he finished 124th on the regular season points list, with 125 qualifying. At the first playoff event, The Barclays at Liberty National Golf Club in New Jersey, he won the event by one stroke, holing a 21-foot putt for par on the last hole to deny Ernie Els, Pádraig Harrington, Steve Stricker, and Tiger Woods the chance of victory. Slocum's win, his third on the Tour, vaulted him 121 spots on the FedEx Cup points list, to 3rd; it also earned him $1,350,000, more than double his prior winnings in 2009. He ended up placing 8th in the FedEx Cup standings that year.
In 2010, Slocum enjoyed a solid year. During the main portion of the season, he recorded four top-ten finishes, including a tie for 4th at The Players Championship. He ended up 46th in the FedEx Cup. Then he capped off his year in style during the Fall Series, winning the inaugural McGladrey Classic. Slocum held off Bill Haas by one stroke to earn the fourth title of his PGA Tour career.
Slocum did not record any top-10 finishes on the PGA Tour in 2011. However, he finished 12th at the Arnold Palmer Invitational, 11th at the U.S. Open, 15th at the McGladrey Classic and 20th at the Children's Miracle Network Hospitals Classic, so he retained his card. In 2012 he had only three top-25 finishes and lost his PGA Tour card. Slocum returned to the PGA Tour Qualifying Tournament but came up just short of reclaiming a Tour card.
In 2013, Slocum split time between the Web.com Tour and PGA Tour, performing poorly on both. He barely qualified for the 2013 Web.com Tour Finals, where he finished 8th at the Chiquita Classic and 17th at the Nationwide Children's Hospital Championship and Web.com Tour Championship, regaining a PGA Tour card for 2014. That season, he had a best result of fourth at the Wyndham Championship but only collected three top-25s, forcing him to return to the Web.com Tour Finals. Once again, though, Slocum saved his PGA Tour card, thanks to a tie for fourth at the Web.com Tour Championship.2001 Buy.com Greater Cleveland Open, Buy.com Knoxville Open, Buy.com Omaha Classic
DNP = Did not playMost consecutive cuts made – 6 (2005 PGA – 2008 Open Championship)
Longest streak of top-10s – 1
World Cup: 2007
CUT = missed the half-way cut
"T" = tied
Yellow background for top-10.