|Aliases HSF2, HSF 2, HSTF 2, heat shock transcription factor 2|
External IDs MGI: 96239 HomoloGene: 37931 GeneCards: HSF2
Heat shock factor protein 2 is a protein that in humans is encoded by the HSF2 gene.
HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Although the names HSF1 and HSF2 were chosen for historical reasons, these peptides should be referred to as heat-shock transcription factors.
HSF2 has been shown to interact with Nucleoporin 62 and HSF1.