Entrez 3298 | Ensembl ENSG00000025156 | |
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Aliases HSF2, HSF 2, HSTF 2, heat shock transcription factor 2 External IDs MGI: 96239 HomoloGene: 37931 GeneCards: HSF2 | ||
Function
HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other species. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Although the names HSF1 and HSF2 were chosen for historical reasons, these peptides should be referred to as heat-shock transcription factors.
Interactions
HSF2 has been shown to interact with Nucleoporin 62 and HSF1.
References
HSF2 Wikipedia(Text) CC BY-SA