Species Human Entrez 3293 | Human Mouse Ensembl ENSG00000130948 | |
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Aliases HSD17B3, EDH17B3, SDR12C2, hydroxysteroid (17-beta) dehydrogenase 3, hydroxysteroid 17-beta dehydrogenase 3 External IDs MGI: 107177 HomoloGene: 20089 GeneCards: HSD17B3 | ||
Testosterone 17-beta-dehydrogenase 3 is an enzyme that in humans is encoded by the HSD17B3 gene.
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
References
HSD17B3 (gene) Wikipedia(Text) CC BY-SA