Species Human Entrez 3219 | Human Mouse Ensembl ENSG00000170689 | |
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Aliases HOXB9, HOX-2.5, HOX2, HOX2E, homeobox B9 External IDs MGI: 96190 HomoloGene: 7367 GeneCards: HOXB9 | ||
Homeobox protein Hox-B9 is a protein that in humans is encoded by the HOXB9 gene.
Contents
Function
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.
Interactions
HOXB9 has been shown to interact with BTG2 and BTG1.
References
HOXB9 Wikipedia(Text) CC BY-SA