Species Human Entrez 3055 | Human Mouse Ensembl ENSG00000101336 | |
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Aliases HCK, JTK9, p59Hck, p61Hck, HCK proto-oncogene, Src family tyrosine kinase External IDs MGI: 96052 HomoloGene: 20489 GeneCards: HCK | ||
Tyrosine-protein kinase HCK is an enzyme that in humans is encoded by the HCK gene.
Contents
Function
The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types, and belongs to the Src family of tyrosine kinases. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
Interactions
HCK has been shown to interact with:
References
HCK Wikipedia(Text) CC BY-SA