Guanylate cyclase coupled receptor

Updated on Dec 13, 2023

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Guanylate cyclase-coupled receptor or Membrane-bound guanylyl cyclase is a single transmembrane protein.

They are enzyme-linked receptors:

GC-A (NPR1/GUCY2A) & GC-B (NPR2/GUCY2B): for natriuretic factors such as atrial natriuretic factor (ANF).

GC-C (GUCY2C): for guanylin and uroguanylin.

GC-D (GUCY2D)

GC-E (GUCY2E)

GC-F (GUCY2F)

There is also a human pseudogene for GUCY2GP.

References

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