Guanidinopropionase

In enzymology, a guanidinopropionase (EC 3.5.3.17) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are 3-guanidinopropanoate and H₂O, whereas its two products are beta-alanine and urea.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is 3-guanidinopropanoate amidinopropionase. Other names in common use include GPase, and GPH. It employs one cofactor, manganese.