Grasso is a surname, and may refer to:
Alexa Grasso, Mexican mixed martial artist
Domenico Grasso, (born 1955) American engineer and educator
Ella T. Grasso, (1919–1981), American politician
Francis Grasso, (1948–2001), American disc jockey
Giulio Grasso (born 1979), developer and technologist
Pietro Grasso, (born 1945), Italian politician
Richard Grasso, chairman and chief executive of the New York Stock Exchange
Stephen Grasso (born 1979), British writer and occultist